Therapy

Therapy

Nourishment

After a nutritional protocol has been established, it is easy to identify the "sins" and

to develop a modification of the lifestyle.


 

 


Medicinal

If sufficient nutritional change is not sufficient to reach the appropriate target
values (table), additional (combination) drug therapy is required.



If a vascular event has already occurred, the drug therapy must be initiated
immediately and maintained for a period of time (under regular control).



arget values of lipid therapy

Parameter

Prevention

Therapy

CH

< 200

< 160

HDL

> 50

> 50

LDL²

< 130

< 100

CH/HDL

< 5

< 3

TG

< 200

< 200

Lp(a)

< 30

< 30

non-HDL-CH*²

< 160

< 130

non HDL-Lp**²

< 190

< 160


CH = Cholesterol;
HDL = high-density Lipoprotein;
LDL = low-density Lipoprotein;
TG= Triglyceride;
Lp(a) = Lipoprotein(a);
  all limits (except CH/HDL) in mg/dl;
CH: 1 mmol/l = 38.7 mg/dl;
TG: 1 mmol/l = 88.6 mg/dl;

* non-HDL-Cholesterol (Cholesterol – HDL cholesterol) is easier and cheaper

to calculate than LDL cholesterol for risk assessment (assessment of a future
vascular event or death);

** the inclusion of Lp (a) for which a value of max. 30 mg / dl is the best way to
take into account the risk of increased Lp (a) for the therapy decision
;

¹optimal: < 150; ²30 Rule (Difference between primary and secondary prevention)


 

 


Lipoprotein Apheresis

In those patients (extremely rare cases) who are unable to achieve the appropriate

target values with a dietary and combined drug therapy, lipoproteinapheresis

(blood wash) is required.


This is usually done at weekly intervals at specialized centers, such as: at ATHOS.

 

 

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